Andrew Corbet Stelzer

Title: **The Contributions of Andrew Corbet Stelzer to Biomolecular Research**

Introduction

Andrew Corbet Stelzer, an innovator based in Ann Arbor, MI, has made significant strides in the field of biomolecular research. With a total of three patents to his name, Stelzer is recognized for his pioneering work in determining the structures of nucleic acids and biomolecules, with a strong focus on applications in drug discovery and chemical biology.

Latest Patents

Stelzer's latest patents showcase advanced methodologies aimed at enhancing our understanding of biomolecular interactions. One notable invention is related to "Small molecule binding pockets in nucleic acids." This technology allows researchers to determine the 2-D or 3-D atomic resolution structure of polynucleotides interacting with small molecules, utilizing NMR and isotopic labeling strategies. Such techniques have vast implications in fields such as drug discovery and the development of chemical biology probes.

Another significant patent is titled "Device and methods for analysis of biomolecule structure, dynamics and activity." This invention presents a method for determining the 3-D atomic resolution structure of biomolecules through chemical shift data obtained from selectively isotopically labeled biomolecule monomers. The methodology also encompasses the use of low-field NMR devices, offering a robust framework for structure determination of various biomolecules, including polynucleotides.

Career Highlights

Stelzer has had a distinguished career, having worked at notable institutions such as Nymirum, Inc. and the University of Michigan. His experience in these organizations has allowed him to collaborate with some of the leading minds in the field of biomolecular research, pushing the boundaries of innovation.

Collaborations

Throughout his career, Stelzer has collaborated with other prominent researchers, including Hashim M Al-Hashimi and Sung-Hun Bae. These partnerships have enabled him to leverage diverse expertise and contribute meaningfully to the advancement of biomolecular science.

Conclusion

Andrew Corbet Stelzer is a distinguished inventor whose work has significantly impacted the understanding of biomolecular structures. His innovative patents serve as a foundation for future advancements in drug discovery and chemical biology. Through his career and collaborations, Stelzer continues to inspire a new wave of research in the scientific community.