The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 12, 2019
Filed:
Dec. 05, 2013
Nymirum, Inc., Ann Arbor, MI (US);
Sung-Hun Bae, Gyeonggi-do, SK;
Aaron Terrence Frank, Ann Arbor, MI (US);
Andrew Corbet Stelzer, San Diego, CA (US);
Hashim M. Al-Hashimi, Chapel Hill, NC (US);
Joshua Paul Fairbank, Chicago, IL (US);
Michael Edward Pape, Ann Arbor, MI (US);
Nymirum, Inc., Ann Arbor, MI (US);
Abstract
The present invention provides a method for determining the 3-dimensional or 3-D atomic resolution structure of a biomolecule using chemical shift data obtained from the biomolecule having one or more selectively isotopically labeled biomolecule monomers and interrogation of same using an NMR device. Methods also comprise use of a low-field NMR device and structure determination method to determine the 2-D and 3-D structure of the biomolecule, for example, a polynucleotide.