Company Filing History:
Years Active: 2005-2009
Title: Andrea E DeBarber: Innovator in Tuberculosis Diagnostics
Introduction
Andrea E DeBarber is a prominent inventor based in Rockville, MD (US). She has made significant contributions to the field of medical diagnostics, particularly in the detection of multidrug-resistant tuberculosis. With a total of 2 patents, her work is crucial in addressing public health challenges.
Latest Patents
One of her latest patents focuses on methods of diagnosing multidrug-resistant tuberculosis. This invention relates to the discovery of a putative gene with no previously identified function, which is responsible for the ability of the bacterium to activate thioamide drugs. The gene, identified as Rv3854c and now termed 'EtaA,' has a low rate of synonymous mutations. All mutations in this gene are expected to inhibit the ability of a bacterium with the mutation to activate a thioamide or thiocarbonyl drug. Therefore, detecting a bacterium with a mutation in this gene indicates that the bacterium is resistant to treatment with thioamides.
Career Highlights
Andrea E DeBarber works at the National Institutes of Health, a component of the US Department of Health & Human Services. Her role at this esteemed institution allows her to contribute to vital research and innovation in the healthcare sector.
Collaborations
Some of her notable coworkers include Clifton E Barry III and Khisimuzi Mdluli. Their collaborative efforts enhance the research and development of effective diagnostic methods.
Conclusion
Andrea E DeBarber's innovative work in tuberculosis diagnostics exemplifies the impact of scientific research on public health. Her contributions are vital in the fight against drug-resistant infections, showcasing the importance of innovation in medicine.