András Mravik

Title: András Mravik: Innovator in Pharmaceutical Chemistry

Introduction

András Mravik is a notable inventor based in Budapest, Hungary. He has made significant contributions to the field of pharmaceutical chemistry, particularly in the production of lumateperone and its salts. His work has led to the development of innovative methods that enhance the efficacy and safety of pharmaceutical compounds.

Latest Patents

Mravik holds two patents related to the production of lumateperone. The first patent describes a method for producing formula (I) lumateperone or its acid addition salts. This method involves separating the enantiomer compound with stereochemistry 6bR,10aS from the cis racemate using resolution. Additionally, the formula (II) stereoisomer is alkylated with 4-halo-4'-fluoro butyrophenone (X=I, Br, Cl) to produce formula (I) lumateperone or its acid addition salt. The invention also covers the amorphous form of the morphologically uniform p-toluenesulfonic acid salt of lumateperone, as well as the naphthalene-2-sulfonic acid salt of lumateperone, including the 1:2 stoichiometry salt formed with naphthalene-2-sulfonic acid.

Career Highlights

Mravik is currently employed at Egis Gyógyszergyár Zrt., a prominent pharmaceutical company in Hungary. His work at Egis has allowed him to focus on innovative drug development and contribute to advancements in the pharmaceutical industry.

Collaborations

Throughout his career, Mravik has collaborated with talented professionals such as Gábor Berecz and Bálint Nyulasi. These collaborations have fostered a creative environment that encourages the exchange of ideas and the development of groundbreaking pharmaceutical solutions.

Conclusion

András Mravik is a distinguished inventor whose work in pharmaceutical chemistry has led to significant advancements in the production of lumateperone. His innovative methods and collaborations continue to impact the field positively.