Location History:
- Kaohsiung, TW (2009 - 2011)
- Taipei, TW (2013 - 2018)
Company Filing History:
6 out of 144 
1 out of 2,085 
1 out of 15,475 
Years Active: 2009-2018
Title: An-Shen Lin: Innovator in Medical Research
Introduction
An-Shen Lin is a prominent inventor based in Kaohsiung, Taiwan. He has made significant contributions to the field of medical research, particularly in the development of compositions for treating various health conditions. With a total of 7 patents to his name, Lin's work showcases his dedication to advancing medical science.
Latest Patents
Among his latest patents, Lin has developed a composition for treating atherosclerosis. This innovative composition includes a chalcone compound that has shown versatile therapeutic potentials. The chalcone compound, which is bound with 2-hydroxyl in ring A and 4'-methoxy in ring B, acts as a PPARγ inducer, p44/42 MAPK inhibitor, and cell cycle blocker. Notably, it does not exhibit toxicity to human aortic smooth muscle cells (HASMCs). Additionally, this compound demonstrates a synergistic effect with the PPARγ ligand, rosiglitazone, to inhibit cell proliferation and the upregulation of cyclin D1, cyclin D3, interleukin-1β (IL-1β), and interleukin-6 (IL-6) induced by oxidized low-density lipoprotein (Ox-LDL). Another significant patent involves compounds and compositions useful in the treatment of malaria, providing methods for treating subjects in need.
Career Highlights
Lin has worked with notable institutions, including Kaohsiung Medical University and Georgia Tech Research Corporation. His research has focused on developing innovative solutions to pressing health issues, demonstrating his commitment to improving patient outcomes through scientific advancements.
Collaborations
Lin has collaborated with esteemed colleagues such as Yang-Chang Wu and Fang-Rong Chang. These partnerships have contributed to the success of his research and the development of his patented inventions.
Conclusion
An-Shen Lin's contributions to medical research and innovation are noteworthy. His patents reflect a commitment to addressing critical health challenges through scientific exploration and collaboration. His work continues to inspire advancements in the medical field.