Company Filing History:
Years Active: 1990-1992
Title: An-Cheng Chang: Innovator in Lipid Vesicle Technology
Introduction
An-Cheng Chang is a notable inventor based in Nashua, NH (US), recognized for his contributions to the field of lipid vesicle technology. With a total of three patents to his name, Chang has made significant advancements in the development of controlled release vehicles and lipid vesicles.
Latest Patents
One of Chang's latest patents is titled "Lipid vesicles having an alkyd as a wall-forming material." This invention features a method for creating lipid vesicles from monomeric and dimeric alkyds, which are esters formed from a first reactant with at least one free hydroxyl group and a C12-C20 fatty acid chain, combined with a second reactant that is an aromatic acid chloride or anhydride. Preferred first reactants include esters and ethers of polyols with C12-C20 fatty acids, as well as C12-C20 fatty alcohols.
Another significant patent is the "Controlled release vehicle," which introduces a new mechanism for controlled release through the breakdown of the entrapping material upon hydration. This vehicle is primarily made from carboxylated cellulose, such as carboxymethylcellulose, treated with a cross-linking agent like aluminum ions and a hydrophobicity agent such as acetic acid. The release agent, which may be cellulase, activates upon hydration to break down the carboxymethylcellulose, thereby releasing the entrapped molecules.
Career Highlights
An-Cheng Chang is currently employed at Micro Vesicular Systems, Inc., where he continues to innovate in the field of lipid vesicle technology. His work has contributed to advancements in drug delivery systems and other applications that require controlled release mechanisms.
Collaborations
Chang has collaborated with notable colleagues, including Donald F. Wallach and S. Esmail Tabibi, who have also contributed to the research and development of innovative technologies in their respective fields.
Conclusion
An-Cheng Chang's work in lipid vesicle technology and controlled release vehicles showcases his innovative spirit and dedication to advancing scientific knowledge. His patents reflect a commitment to improving drug delivery systems and enhancing the efficacy of various applications.