Amrita Pati

Title: Amrita Pati: Innovator in Microsatellite Instability Detection

Introduction

Amrita Pati is a notable inventor based in San Ramon, CA (US). She has made significant contributions to the field of genomic research, particularly in the detection of microsatellite instability (MSI). Her innovative work has implications for cancer research and diagnostics.

Latest Patents

Amrita Pati holds a patent for the "Detection of microsatellite instability." This patent outlines methods and systems for detecting MSI, which include enriching human genomic DNA for microsatellite loci. The patent also describes an oligonucleotide array for detecting MSI. The method involves detecting sequencing reads from a sample for various microsatellite loci, determining a metric for repeat length distribution (RLD) for each locus, and comparing this metric to a threshold value. Furthermore, it quantifies the number of microsatellite loci exceeding the threshold and compares this to a microsatellite instability proportion threshold.

Career Highlights

Throughout her career, Amrita has worked with prominent companies in the biotechnology sector, including Roche Sequencing Solutions, Inc. and Roche Diagnostics GmbH. Her experience in these organizations has allowed her to develop and refine her expertise in genomic technologies.

Collaborations

Amrita has collaborated with notable colleagues such as Seyed Hamid Mirebrahim and Alexander Lovejoy. These collaborations have contributed to her innovative research and advancements in the field.

Conclusion

Amrita Pati is a pioneering inventor whose work in detecting microsatellite instability is paving the way for advancements in genomic research and cancer diagnostics. Her contributions are invaluable to the scientific community and continue to influence the field.