Amrit Raj Ghosh

Title: Amrit Raj Ghosh: Innovator in Immune Response Modulation

Introduction

Amrit Raj Ghosh is a notable inventor based in Jadavpur, India. He has made significant contributions to the field of immunology through his innovative research and development of pharmaceutical agents. His work focuses on the modulation of immune responses, particularly in relation to toll-like receptors.

Latest Patents

Ghosh holds a patent for his invention titled "Blocking toll-like receptor 9 signaling with small molecule antagonist." This invention relates to small molecule 4-(piperazin-1-yl)quinazolin-2-amino compounds, which are useful for inhibiting signaling by certain toll-like receptors, especially TLR9. Toll-like receptors are critical components of the immune system, playing a vital role in distinguishing between self and non-self entities. Aberrant activation of TLR9 is linked to various autoimmune diseases, making Ghosh's invention particularly relevant for clinical applications. The compounds described in his patent can be utilized as pharmaceutical agents to treat conditions involving unwanted immune activity due to TLR9 activation.

Career Highlights

Amrit Raj Ghosh is affiliated with the Council of Scientific & Industrial Research, where he continues to advance his research in immunology. His work has garnered attention for its potential to impact the treatment of autoimmune diseases and improve patient outcomes.

Collaborations

Ghosh collaborates with esteemed colleagues, including Arindam Talukdar and Dipyaman Ganguly. Their combined expertise enhances the research efforts and contributes to the development of innovative solutions in the field of immunology.

Conclusion

Amrit Raj Ghosh is a pioneering inventor whose work in blocking toll-like receptor signaling represents a significant advancement in immunology. His contributions have the potential to lead to new therapeutic strategies for managing autoimmune diseases.