Company Filing History:
Years Active: 2020-2023
Title: Amnon Altman: Innovator in Immune Response Modulation
Introduction
Amnon Altman is a prominent inventor based in La Jolla, California. He has made significant contributions to the field of immunology, particularly in the modulation of immune responses. With a total of two patents to his name, Altman's work focuses on innovative methods and compositions that have the potential to transform therapeutic approaches for various diseases.
Latest Patents
Altman's latest patents include groundbreaking research on peptides and methods related to ICOS signaling. This patent discloses methods and compositions that are useful for initiating and propagating ICOS-mediated signaling. Specifically, it provides three peptide motifs that promote ICOS binding, and their ablation leads to modulated ICOS signaling. This modulation can affect signaling mediated by TBK1, IRF4, IKKβ, or TBKBP1. The binding of these peptide motifs or their addition as co-stimulatory agents can lead to modulated immune responses, offering new therapies for neurodegenerative, autoimmune, metabolic, cancer inflammatory, or immunodeficiency conditions.
Another significant patent focuses on the modulation of T cell signaling via SLAT association with IP3R1. This patent outlines methods for modulating immune responses by contacting SLAT or IP3R1 with agents that influence their binding. It also includes methods for modulating the activation or differentiation of CD4+ T cells, providing further insights into immune system regulation.
Career Highlights
Amnon Altman is affiliated with the La Jolla Institute for Allergy and Immunology, where he conducts his research. His work is characterized by a commitment to advancing the understanding of immune mechanisms and developing innovative therapeutic strategies.
Collaborations
Altman collaborates with notable colleagues such as Kok-Fai Kong and Shane Crotty, contributing to a dynamic research environment that fosters innovation and discovery.
Conclusion
Amnon Altman's contributions to immunology through his patents and research at the La Jolla Institute for Allergy and Immunology highlight his role as a key innovator in the field. His work has the potential to lead to significant advancements in the treatment of various immune-related conditions.