The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2020
Filed:
May. 01, 2015
Applicant:
LA Jolla Institute for Allergy and Immunology, La Jolla, CA (US);
Inventor:
Amnon Altman, La Jolla, CA (US);
Assignee:
LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY, La Jolla, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); C07K 16/28 (2006.01); C07K 14/205 (2006.01); A61K 38/00 (2006.01); A61K 38/17 (2006.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
C07K 16/28 (2013.01); A61K 38/00 (2013.01); A61K 38/17 (2013.01); A61K 38/177 (2013.01); C07K 14/705 (2013.01); C07K 16/18 (2013.01); A61K 2300/00 (2013.01); C07K 2317/34 (2013.01); C07K 2317/76 (2013.01);
Abstract
Methods of modulating immune responses are provided, including contacting SLAT or IP3R1 with an agent that modulates binding of SLAT to IP3R1. Methods of modulating activation or differentiation of CD4+ T cells are also provided, including contacting SLAT or IP3R1 with an agent that modulates binding of SLAT to IP3R1. Peptides and fragments of an IP3R1 amino acid sequence that binds to a SLAT amino acid sequence, and peptides and fragments of a SLAT amino acid sequence that binds to am IP3R1 amino acid sequence, are further provided.