Company Filing History:
Years Active: 2002-2004
Title: Innovations by Inventor Amit Tewari
Introduction
Amit Tewari is a notable inventor based in Lucknow, India. He has made significant contributions to the field of pharmaceuticals, particularly in the development of methods for synthesizing important antimalarial drugs. With a total of 3 patents to his name, Tewari's work is recognized for its innovative approaches and practical applications.
Latest Patents
One of Tewari's latest patents is titled "Single pot conversion of artemisinin into arteether." This invention provides a method for the preparation of arteether from artemisinin in a single pot within approximately four hours. The process involves the reduction of artemisinin into dihydroartemisinin using a minimal amount of sodium borohydride in ethanol at room temperature, along with a novel polyhydroxy catalyst. The method further includes the acylation of dihydroartemisinin in the presence of an acid catalyst, followed by the extraction of arteether from an aqueous reaction mixture using 1% ethyl acetate in n-hexane. The final workup and purification yield 80-86% (w/w) pure alpha, beta arteether.
Another significant patent by Tewari is "Single pot conversion of artemisinin into artemether." This improved method for preparing artemether is particularly useful for treating uncomplicated, severe complicated, and multi-drug resistant malaria. The efficiency and effectiveness of this process highlight Tewari's commitment to addressing critical health challenges.
Career Highlights
Amit Tewari is associated with the Council of Scientific and Industrial Research, where he continues to contribute to research and development in the pharmaceutical sector. His work has not only advanced scientific knowledge but has also provided practical solutions for pressing health issues.
Collaborations
Tewari has collaborated with esteemed colleagues such as Rajendra Singh Bhakuni and Atul Prakash Kahol. These partnerships have fostered a collaborative environment that enhances innovation and research outcomes.
Conclusion
Amit Tewari's contributions to the field of pharmaceuticals through his innovative patents demonstrate his dedication to improving healthcare solutions. His work in synthesizing antimalarial drugs is a testament to the impact of scientific research on global health challenges.