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Years Active: 2025
Title: Innovations in Tissue Engineering by Amir Sheikhi
Introduction
Amir Sheikhi is an accomplished inventor based in State College, PA (US). He has made significant contributions to the field of tissue engineering, particularly through his innovative patents. With a total of 3 patents, Sheikhi is recognized for his work in developing advanced materials for medical applications.
Latest Patents
One of Amir Sheikhi's latest patents is focused on tough tissue sealants and their use. This invention provides injectable, tough hydrogels that can be crosslinked in situ on demand using minimally-invasive methods, such as visible light exposure. The invention addresses an unmet medical challenge by utilizing gelatin methacryloyl (GelMA), a naturally-derived biopolymer known for its excellent bioadhesion, biodegradation, and biocompatibility. To overcome the brittleness of GelMA, Sheikhi hybridized it with methacrylate-modified alginate (AlgMA), resulting in hydrogels that exhibit ion-induced reversible crosslinking. This innovation leads to a photocrosslinkable, injectable, and adhesive platform with improved toughness, making it suitable for durable tissue sealants in minimally invasive procedures.
Another notable patent by Sheikhi involves methods for fabricating modular hydrogels from macromolecules with orthogonal physico-chemical responsivity. This invention addresses the limitations of stiff, flowable hydrogels in 3D cellular engineering. By developing a universal method to convert macromolecules into annealable building blocks, Sheikhi has created 3D microporous beaded scaffolds that promote cell functionality and rapid 3D seeding.
Career Highlights
Amir Sheikhi has worked with prestigious institutions, including the University of California and the Mayo Foundation for Medical Education and Research. His work has significantly advanced the field of tissue engineering and has the potential to improve patient outcomes in various medical applications.
Collaborations
Some of his notable coworkers include Alireza Khademhosseini and Rahmi Oklu. Their collaborative efforts have contributed to the development of innovative solutions in the field of biomedical engineering.
Conclusion
Amir Sheikhi's contributions to tissue engineering through his innovative patents demonstrate his commitment to advancing medical technology. His work in developing tough tissue sealants and modular hydrogels is paving the way for new