Company Filing History:
Years Active: 2014-2016
Title: Amanda Barbara MacKenzie: Innovator in Glycosylation Technologies
Introduction
Amanda Barbara MacKenzie is a prominent inventor based in Bath, GB. She has made significant contributions to the field of glycosylation, holding a total of 3 patents. Her work focuses on developing materials and methods that enhance the biological properties of therapeutic moieties.
Latest Patents
One of her latest patents is titled "Materials and methods relating to glycosylation." This patent describes techniques for producing glycosylation structures that are resistant to enzymatic degradation. This innovation modulates the biological properties of therapeutic moieties that incorporate these structures. Specifically, it involves reacting activated carbohydrate substrates containing fluorine, such as 3-fluoro sialic acid compounds, with sugar acceptors to create covalent conjugates.
Another significant patent is "Functionalizing reagents and their uses." This patent discloses reagents and methods for functionalizing polypeptides with moieties, such as alkylene glycol molecules and glycan groups. The functionalizing reagent comprises a nitrogen-containing heterocyclic aromatic ring with a vinyl substituent that reacts with thiol groups present in polypeptides. This reaction covalently links the polypeptide to poly(alkylene glycol) molecules or glycan groups, enhancing their functionality.
Career Highlights
Amanda is currently associated with Glythera Limited, where she continues to innovate in the field of glycosylation. Her work has positioned her as a key player in the development of therapeutic technologies.
Collaborations
She collaborates with notable colleagues, including Andrew Graham Watts and Terrence Kantner, contributing to advancements in their shared field of research.
Conclusion
Amanda Barbara MacKenzie is a trailblazer in glycosylation technologies, with a focus on enhancing therapeutic applications. Her innovative patents and collaborations reflect her commitment to advancing scientific knowledge and improving healthcare solutions.