The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 27, 2016
Filed:
Jun. 16, 2010
Applicants:
Andrew Graham Watts, Bath, GB;
Amanda Barbara Mackenzie, Bath, GB;
Terrence Kantner, Bath, GB;
Inventors:
Assignee:
Glythera Limited, Newcastle Upon Tyne, GB;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 5/06 (2006.01); C07K 14/47 (2006.01); C07K 14/555 (2006.01); C07K 14/54 (2006.01); C07K 14/52 (2006.01); A61K 31/7008 (2006.01); C07K 14/62 (2006.01); C07K 14/61 (2006.01); C07K 1/107 (2006.01); C07K 14/53 (2006.01); C12P 19/26 (2006.01); C07K 16/00 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
A61K 47/4823 (2013.01); A61K 47/48092 (2013.01);
Abstract
Techniques to glycosylation are described, and more particularly to the production of glycosylation structures that are resistant to enzymatic degradation, thereby modulating one or more of their biological properties or those of therapeutic moieties incorporating them, and in particular to reacting activated carbohydrate substrates containing fluorine, such as 3-fluoro sialic acid compounds, with sugar acceptors to produce covalent conjugates of the sugar acceptor and one or more of the sialic acid compounds.