Vleuten, Netherlands

Alphonsus G C M UytdeHaag


Average Co-Inventor Count = 2.4

ph-index = 5

Forward Citations = 102(Granted Patents)


Location History:

  • De Bilt, NL (2007)
  • Utrecht, NL (2007)
  • Vleuten, NL (2007 - 2011)

Company Filing History:


Years Active: 2007-2011

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10 patents (USPTO):Explore Patents

Title: Innovations in Vaccine Production by Alphonsus G C M UytdeHaag

Introduction

Alphonsus G C M UytdeHaag is a notable inventor based in Vleuten, Netherlands. He has made significant contributions to the field of biotechnology, particularly in the production of vaccines and recombinant proteins. With a total of 10 patents to his name, UytdeHaag's work has the potential to revolutionize vaccine manufacturing processes.

Latest Patents

One of UytdeHaag's latest patents focuses on the production of vaccines through innovative methods for producing mammalian viruses. This method involves infecting a culture of immortalized human cells with a virus and incubating the culture to propagate the virus. The resulting virus-containing medium can be harvested for vaccine production. This approach offers several advantages, including the ability to culture human cells under defined serum-free conditions, which enhances the capability for virus propagation. Additionally, UytdeHaag has developed methods for producing influenza virus and vaccines derived from cultured human cells, eliminating the need for whole chicken embryos in vaccine production. Another significant patent involves producing erythropoietin isoforms with increased sialylation, utilizing immortalized human embryonic retina cells.

Career Highlights

UytdeHaag is currently associated with Crucell Holland B.V., where he continues to advance his research and innovations. His work has been instrumental in developing methods that allow for large-scale continuous production of viruses, which is crucial for meeting global vaccine demands.

Collaborations

UytdeHaag collaborates with esteemed colleagues such as Maria Grazia Pau and Govert Johan Schouten. Their combined expertise contributes to the success of their innovative projects and research initiatives.

Conclusion

Alphonsus G C M UytdeHaag's contributions to vaccine production and biotechnology are noteworthy. His innovative methods and patents have the potential to significantly impact public health and vaccine accessibility.

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