This inventor holds 2 USPTO granted patents. Top assignee: University of Southern California. Active years: 2013-2017.
Company Filing History:
Years Active: 2013-2017
Title: **Innovative Contributions of Allen S Yang in DNA Methylation Research**
Introduction
Allen S Yang, an accomplished inventor based in Valencia, California, has made significant contributions to the field of genetics through his innovative patents. With a focus on DNA methylation and its applications in gene regulation, Yang's work is vital for advancing our understanding of epigenetics and its implications in health and disease.
Latest Patents
Yang holds two notable patents that showcase his expertise in DNA methylation haplotyping and detection methods. The first patent, titled "High throughput method of DNA methylation haplotyping," outlines novel approaches for quantifying DNA methylation at a single-base resolution. This innovative method uses allele-specific sequence polymorphisms in close proximity to CpG methylation sites, enabling the differentiation of methylation levels between alleles. Methods such as PCR amplification and allele-specific pyrosequencing are at the core of this patent, allowing for detailed quantitative analyses related to gene expression and clinical conditions like loss of imprinting (LOI).
The second patent, “Detection of methylated DNA and DNA mutations,” presents various techniques for detecting DNA methylation and defective DNA. This invention features a nanosensor designed to bind with probes complementary to specific DNA methylation sequences, enhancing the sensitivity and accuracy of detection methods in genetic research.
Career Highlights
Allen S Yang is affiliated with the University of Southern California, where he leverages his research to push the boundaries of genetic science. His patents are a testament to his innovative approach to complex biological questions, reflecting years of dedicated research and exploration in genetic methodologies.
Collaborations
Yang's innovative work has fostered collaborations with notable researchers, including Mihaela Campan and Peter W Laird. Their combined efforts contribute to a richer understanding of DNA methylation and its impact on various biological processes, reinforcing the importance of teamwork in scientific discovery.
Conclusion
In conclusion, Allen S Yang's contributions to the field of DNA methylation through his patents and collaborative efforts at the University of Southern California underscore his role as an influential inventor in genetics. His innovative methods for analyzing DNA methylation not only advance scientific research but also pave the way for potential applications in medicine and diagnostics.