Alison D O'Brien

Title: Innovations of Alison D O'Brien

Introduction

Alison D O'Brien is a prominent inventor based in Bethesda, MD (US). She has made significant contributions to the field of medical research, particularly in the area of Shiga toxin type 2 protein. With a total of 9 patents to her name, her work has the potential to impact the treatment of diseases associated with this toxin.

Latest Patents

Her latest patents focus on methods and compositions based on Shiga toxin type 2 protein. The invention is based on the discovery of the epitope in the Stx2 protein for the 11 E1O antibody. It features compositions containing non-full length Stx2 polypeptides that include the 11 E1O monoclonal antibody epitope. Additionally, the invention outlines methods of producing anti-Stx2 antibodies specific for the 11 E1O epitope of the Stx2 protein. Furthermore, it includes methods for treating subjects who have, or are at risk of developing, Shiga toxin-associated diseases, such as hemolytic uremic syndrome. The invention also provides techniques for detecting Stx2 in samples using the antibodies developed through these methods.

Career Highlights

Throughout her career, Alison has worked with notable organizations, including the Henry M. Jackson Foundation for the Advancement of Military Medicine and Sunol Molecular Corporation. Her work in these institutions has allowed her to advance her research and contribute to significant medical innovations.

Collaborations

Alison has collaborated with several professionals in her field, including Angela Ruth Melton-Celsa and Michael Smith. These collaborations have enriched her research and expanded the impact of her inventions.

Conclusion

Alison D O'Brien's contributions to the field of medical research through her patents on Shiga toxin type 2 protein demonstrate her innovative spirit and dedication to improving health outcomes. Her work continues to pave the way for advancements in the treatment of related diseases.