This inventor holds 1 USPTO granted patent. Top assignees: Biology Centre as Cr, V.v.i., Institute for Clinical and Experimental Medicine, Institute of Microbiologyh as Cr, V.v.i.. Active years: 2016.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
1 out of 3 
1 out of 1 
1 out of 1 Years Active: 2016
Title: Alica Chronakova: Innovator in Anti-Inflammatory Metabolites
Introduction
Alica Chronakova is a notable inventor based in Pisek, Slovakia. She has made significant contributions to the field of microbiology and biochemistry, particularly through her innovative work on manumycin-type metabolites. Her research has the potential to impact the development of anti-inflammatory agents.
Latest Patents
Alica Chronakova holds a patent for a manumycin-type metabolite called Colabomycin E. This compound inhibits caspase 1 and the creation of interleukins. The strain that produces Colabomycin E is SOK1/5-04, which has been deposited in The Czech collection of microorganisms under the number CCM8556. Colabomycin E is structurally similar to the known metabolite colabomycin A, but features a polyene chain that is two carbons longer. Biological activity assays have shown that Colabomycin E significantly inhibits IL-1β release from THP-1 cells, indicating its potential as an anti-inflammatory agent.
Career Highlights
Throughout her career, Alica Chronakova has worked at esteemed institutions such as the Biology Centre and the Institute of Microbiology, both as part of the Czech Republic's research community. Her work has focused on the exploration of microbial metabolites and their applications in medicine.
Collaborations
Alica has collaborated with notable colleagues, including Miroslav Petricek and Katerina Petrickova. These partnerships have contributed to her research and the advancement of her innovative projects.
Conclusion
Alica Chronakova's work on Colabomycin E exemplifies her commitment to advancing scientific knowledge in the field of anti-inflammatory agents. Her contributions are paving the way for future research and potential therapeutic applications.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile