Algis Anilionis

Title: Algis Anilionis: Innovator in Bacterial Gene Expression

Introduction

Algis Anilionis is a notable inventor based in Pittsford, NY (US), recognized for his contributions to the field of biotechnology. He holds five patents, showcasing his innovative approach to solving complex problems in bacterial gene expression.

Latest Patents

One of his latest patents is titled "Stable pura vectors and uses therefor." This invention pertains to a complementation system for the selection and maintenance of expressed genes in bacterial hosts. The invention provides stable vectors that can be selected and maintained by complementation of chromosomal deletion mutations of purA (adenylosuccinate synthetase), obviating the use of antibiotic resistance genes. This system is particularly useful in production organisms during fermentation and in live vaccine bacteria, such as attenuated Salmonella typhi. It allows for the selection of chromosomal integrants and for the stable maintenance of plasmids in the vaccinated host without the application of external selection pressure.

Career Highlights

Throughout his career, Algis Anilionis has worked with several prominent companies, including Praxis Biologics, Inc. and American Cyanamid Company. His work has significantly impacted the field of biotechnology, particularly in the development of innovative solutions for gene expression in bacterial systems.

Collaborations

Algis has collaborated with notable professionals in his field, including Robert N Brey, III and James P Fulginiti. These collaborations have further enhanced his contributions to biotechnology and innovation.

Conclusion

Algis Anilionis stands out as a significant figure in the realm of biotechnology, with a focus on bacterial gene expression and innovative solutions. His patents and career achievements reflect his dedication to advancing the field.