This inventor holds 9 USPTO granted patents and 1 published patent application and 2 EPO patents. Top assignees: The United States of America, as Represented by the Secretary, Department of Health and Human Services, Other. Active years: 2001-2011.
Location History:
- Washington, DC (US) (2001)
- 26144 Galilea, La Rioja, ES (2008)
- Bethesda, MD (US) (2008)
- McLean, VA (US) (2006 - 2011)
- La Rioja, ES (2009 - 2011)
Company Filing History:
8 out of 3,690 
1 out of 834,411 Years Active: 2001-2011
Title: The Innovative Contributions of Alfredo Martinez
Introduction
Alfredo Martinez is a notable inventor based in McLean, VA (US), recognized for his significant contributions to the field of biomedical research. He holds a total of 9 patents, showcasing his innovative approach to addressing complex medical challenges. His work primarily focuses on the role of adrenomedullin (AM) in human pathology and physiology.
Latest Patents
Martinez's latest patents include groundbreaking methods for the isolation, identification, and purification of AM-binding proteins. One of his key inventions provides methods for utilizing these purified proteins to diagnose, treat, and monitor AM-related diseases, such as those associated with abnormally elevated AM levels. Additionally, he has identified a complex between AM and a specific AM-binding protein, factor H (fH), which has implications for treating conditions like cancer and diabetes. His research demonstrates that AM acts as a universal autocrine growth factor in human cancer cell lines, driving neoplastic proliferation. The methods he developed also include experimental models for understanding the role of AM in pancreatic physiology, revealing that AM inhibits insulin secretion in a dose-dependent manner.
Career Highlights
Throughout his career, Alfredo Martinez has worked with prestigious organizations, including the National Institutes of Health, a component of the US Department of Health & Human Services. His innovative research has led to advancements in therapeutic, pharmacologic, and physiologic compositions that utilize AM peptides and antibodies.
Collaborations
Martinez has collaborated with esteemed colleagues such as Frank Cuttitta and William G Stetler-Stevenson, contributing to the advancement of knowledge in his field.
Conclusion
Alfredo Martinez's contributions to biomedical research and his innovative patents have significantly impacted the understanding and treatment of various diseases. His work continues to inspire advancements in medical science and therapeutic approaches.