The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 2008
Filed:
Oct. 03, 2003
Frank Cuttitta, Adamstown, MD (US);
Alfredo Martinez, Bethesda, MD (US);
William G. Stetler-stevenson, Kensington, MD (US);
Edward J. Unsworth, Kensington, MD (US);
Juan M. Saavedra, Bethesda, MD (US);
Frank Cuttitta, Adamstown, MD (US);
Alfredo Martinez, Bethesda, MD (US);
William G. Stetler-Stevenson, Kensington, MD (US);
Edward J. Unsworth, Kensington, MD (US);
Juan M. Saavedra, Bethesda, MD (US);
Abstract
Methods and compounds are described for regulating blood pressure in a subject. Specific embodiments are methods for reversing vasodilation of blood vessels, by administering to a subject a therapeutically effective amount peptide AM(11-22). The vasoconstrictor can be used for a variety of purposes, including hemostasis or the treatment of shock, for example vasodilatory shock syndromes such as septic shock. Other specific embodiments are methods for reversing vasoconstriction of blood vessels, by administering to a subject a therapeutically effect amount of an inhibitor of AM(11-22), sufficient to reduce hypertension in the subject. Compounds and pharmaceutical compositions are also provided, as are kits.