Jerusalem, Israel

Alexei Shir

USPTO Granted Patents = 8 

 

Average Co-Inventor Count = 3.0

ph-index = 3

Forward Citations = 14(Granted Patents)


Company Filing History:


Years Active: 2011-2023

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8 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Inventor Alexei Shir

Introduction: Alexei Shir, an accomplished inventor based in Jerusalem, Israel, has made significant strides in the field of cancer treatment. With a total of eight patents to his name, he is recognized for his groundbreaking inventions aimed at combating serious health issues, particularly castration-resistant prostate cancer.

Latest Patents: Among his latest innovations, Alexei Shir has developed a unique polyplex that plays a crucial role in the treatment of castration-resistant prostate cancer (CRPC). This invention involves a combination of double-stranded RNA (dsRNA) and a polymeric conjugate made up of a linear polyethyleneimine (LPEI), polyethylene glycol (PEG) moieties, linkers, and targeting moieties. The targeting moieties are designed to bind to prostate surface membrane antigen (PSMA), allowing for targeted cancer therapy. Furthermore, his methodology for administering this polyplex represents a significant advancement in cancer treatment, offering new avenues for therapeutic intervention.

Career Highlights: Throughout his career, Shir has worked with prominent organizations, such as Targimmune Therapeutics AG and Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. His experiences in these companies have significantly contributed to his expertise and the successful development of his patented technologies.

Collaborations: Alexei Shir has collaborated with esteemed colleagues, including Alexander Levitzki and Maya Zigler. Their combined efforts have fostered an environment of innovation, contributing to advancements in cancer research and treatment methodologies.

Conclusion: With a total of eight patents and a focus on innovative cancer treatment, Alexei Shir continues to push the boundaries of medical science. His work, particularly in the realm of castration-resistant prostate cancer, highlights the potential of targeted therapies in improving patient outcomes. Innovators like Shir pave the way for future discoveries and advancements in the fight against cancer.

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