The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 2022
Filed:
Mar. 07, 2019
Applicant:
Targimmune Therapeutics Ag, Basel, CH;
Inventors:
Alex Levitzki, Jerusalem, IL;
Salim Joubran, Lod, IL;
Alexei Shir, Jerusalem, IL;
Maya Zigler, Neve Ilan, IL;
Alaa Talhami, Maghar Village, IL;
Yael Langut, Haifa, IL;
Assignee:
TARGIMMUNE THERAPEUTICS AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/14 (2015.01); A61K 45/06 (2006.01); C12N 15/117 (2010.01); A61K 47/60 (2017.01); A61K 47/59 (2017.01); A61K 35/17 (2015.01);
U.S. Cl.
CPC ...
A61K 35/14 (2013.01); A61K 45/06 (2013.01); A61K 47/59 (2017.08); A61K 47/60 (2017.08); C12N 15/117 (2013.01); A61K 35/17 (2013.01); C12N 2310/17 (2013.01); C12N 2310/351 (2013.01); C12N 2310/53 (2013.01);
Abstract
A method of treating cancer can include administering a polyplex of a double stranded RNA and a polymeric conjugate. The polymeric conjugate can consist of a linear polyethyleneimine covalently linked to one or more polyethylene glycol (PEG) moieties. Each PEG moiety can be conjugated via a linker to a targeting moiety capable of binding to a cancer antigen.