Company Filing History:
Years Active: 2012
Title: Alexandra Scherleithner: Innovator in Pharmaceutical Chemistry
Introduction
Alexandra Scherleithner is a notable inventor based in Neufeld/Leitha, Austria. She has made significant contributions to the field of pharmaceutical chemistry, particularly in the production of high-purity compounds. Her innovative methods have the potential to impact the pharmaceutical industry positively.
Latest Patents
Scherleithner holds a patent for a method for the production of high-purity 4a, 5, 9, 10, 11, 12,-hexahydro-6H-benzofuro [3a, 3, 2-ef] [2] benzazepine and its derivatives. This process provides a way to produce extremely pure galanthamine and galanthamine derivatives. The method involves debrominating racemic bromine narwedine under palladium catalysis. The reaction mixture is then worked up in the presence of oxygen or peroxides, converting the palladium catalyst into an insoluble form that can be easily separated. Further reactions include the reduction of enantiomerically pure narwedine to form enantiomerically pure galanthamine, which can then be alkylated or dealkylated to achieve a corresponding substitution on the ring-nitrogen atom. The process ensures that residual portions of palladium are below 5 ppm, allowing the pure galanthamine to be used directly as a pharmaceutical raw material.
Career Highlights
Scherleithner is currently associated with Sanochemia Pharmazeutika AG, where she continues to develop her innovative methods. Her work has garnered attention for its potential applications in the pharmaceutical sector, particularly in the production of high-purity compounds that are essential for drug formulation.
Collaborations
Some of her notable coworkers include Stefan Welzig and Anton Gerdenitsch. Their collaborative efforts contribute to the advancement of research and development in pharmaceutical chemistry.
Conclusion
Alexandra Scherleithner is a pioneering inventor whose work in pharmaceutical chemistry is making a significant impact. Her innovative methods for producing high-purity compounds are essential for the advancement of the pharmaceutical industry.