Company Filing History:
Years Active: 2025
Title: Innovations by Inventor Alexandra D'ordine
Introduction
Alexandra D'ordine is a notable inventor based in Lakeville, MA (US). She has made significant contributions to the field of medical research, particularly in the area of age-associated inflammation and disorders. With a total of 2 patents, her work focuses on innovative methods for treating and preventing age-related health issues.
Latest Patents
D'ordine's latest patents include compositions and methods for treating, preventing, or reversing age-associated inflammation and disorders. One of her patents discloses a method for preventing, delaying, or reversing age-associated inflammation by administering a therapeutically effective amount of at least one LINE 1 (L-1) endonuclease inhibitor. This method addresses the upregulation of L1, accumulation of cytoplasmic L1 cDNA, activation of an IFN-I response, and reinforcement of a SASP pro-inflammatory state. The L1 EN inhibitor is administered in an amount sufficient to prevent or reverse these conditions. Another patent outlines similar methods, emphasizing the administration of L1 EN inhibitors, either alone or in combination with additional therapeutic agents, to measure effectiveness via biomarkers and symptom reduction.
Career Highlights
Alexandra D'ordine is affiliated with Brown University, where she conducts her research and develops her innovative solutions. Her work has garnered attention for its potential impact on aging and related health challenges.
Collaborations
D'ordine collaborates with esteemed colleagues such as John M Sedivy and Gerwald Jogl, contributing to a rich environment of research and innovation.
Conclusion
Alexandra D'ordine's contributions to the field of medical research through her patents highlight her commitment to addressing age-associated health issues. Her innovative methods have the potential to significantly improve the quality of life for many individuals.