Alexander Marson

Title: Innovations of Alexander Marson

Introduction

Alexander Marson is a prominent inventor based in San Francisco, CA. He has made significant contributions to the field of biomedical research, particularly in the area of genome editing and T cell receptor engineering. With a total of 12 patents to his name, Marson's work is at the forefront of innovative medical technologies.

Latest Patents

Among his latest patents is the "Targeted replacement of endogenous T cell receptors." This patent outlines methods and compositions for editing the genome of human T cells. In some embodiments, a heterologous T cell receptor (TCR)-β chain and a heterologous TCR-α chain are inserted into exon 1 of a TCR subunit constant gene in the genome of the T cell. Another notable patent is for "Compositions and methods for modifying a target nucleic acid." This disclosure provides compositions and methods for modifying a target nucleic acid, which can include a targetable nuclease, a DNA-binding protein, and a donor template comprising a homology directed repair (HDR) template and one or more DNA-binding protein target sequences.

Career Highlights

Marson has worked with prestigious institutions such as the University of California and the Whitehead Institute for Biomedical Research. His research has significantly advanced the understanding of T cell biology and genome editing techniques.

Collaborations

Some of his notable coworkers include Theodore Lee Roth and Eric Shifrut. Their collaborative efforts have contributed to the success of various research projects and innovations in the field.

Conclusion

Alexander Marson's innovative work in genome editing and T cell receptor engineering has positioned him as a leading inventor in biomedical research. His contributions continue to pave the way for advancements in medical technology and therapeutic applications.