The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 15, 2025
Filed:
Dec. 12, 2019
The Regents of the University of California, Oakland, CA (US);
Alexander Marson, Oakland, CA (US);
Theodore Lee Roth, Oakland, CA (US);
Daniel Goodman, Oakland, CA (US);
David-Huy Nhu Nguyen, Oakland, CA (US);
Francis C. Szoka, Jr., Oakland, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
The disclosure provides compositions and methods for modifying a target nucleic acid. In some embodiments, a composition can include a targetable nuclease, a DNA-binding protein, and a donor template comprising a homology directed repair (HDR) template and one or more DNA-binding protein target sequences. In some embodiments, a composition can include a Cas protein, one or more single guide RNAs (sgRNAs), and an anionic polymer.