Alexander J Reif

Title: Innovations of Alexander J Reif

Introduction

Alexander J Reif is a notable inventor based in Holland, PA (US). He has made significant contributions to the field of pharmaceuticals, particularly in the development of compounds that target neurological and psychiatric disorders. With a total of 3 patents, his work has the potential to impact the treatment of various diseases associated with glutamate dysfunction.

Latest Patents

One of his latest patents involves imidazopyridin-2-one derivatives. This invention is directed to compounds that act as potentiators of metabotropic glutamate receptors, specifically the mGluR receptor. These compounds are useful in the treatment or prevention of neurological and psychiatric disorders linked to glutamate dysfunction. Additionally, the invention includes pharmaceutical compositions that utilize these compounds for therapeutic purposes.

Another significant patent by Reif focuses on positive allosteric modulators of the mGluR2 receptor. This invention encompasses benzimidazolone derivatives that serve as positive allosteric modulators, which are beneficial in treating or preventing neurological and psychiatric disorders associated with glutamate dysfunction. The patent also covers pharmaceutical compositions that incorporate these compounds for the prevention or treatment of diseases such as schizophrenia.

Career Highlights

Alexander J Reif is currently employed at Merck Sharp & Dohme Corporation, a leading global healthcare company. His work at Merck has allowed him to collaborate with other talented professionals in the field, contributing to innovative solutions in pharmaceutical development.

Collaborations

Some of his notable coworkers include Mark E Layton and Joseph E Pero. Their collaborative efforts have further advanced the research and development of compounds aimed at addressing critical health issues.

Conclusion

Alexander J Reif's contributions to the field of pharmaceuticals through his innovative patents highlight his commitment to improving treatments for neurological and psychiatric disorders. His work continues to pave the way for advancements in medical science and patient care.