Location History:
- Gurnee, IL (US) (1980 - 1986)
- Libertyville, IL (US) (1990 - 1993)
- San Diego, CA (US) (1994 - 2003)
Company Filing History:
9 out of 134 
7 out of 4,177 
1 out of 832,680 Years Active: 1980-2003
Title: **Innovative Contributions of Alex M Nadzan in Retinoid Research**
Introduction
Alex M Nadzan is a notable inventor based in San Diego, California, whose work has significantly impacted the field of retinoid research. With a remarkable portfolio of 17 patents, Nadzan's innovations primarily focus on compounds that modulate processes mediated by retinoid X receptors. His expertise has led to advancements that could unlock new therapeutic pathways for various medical applications.
Latest Patents
Among his latest patents, Nadzan has developed compounds demonstrating selective activity for retinoid X receptors (RXRs). This includes compositions and methods for modulating processes mediated by RXRs, emphasizing the potential of retinoid-like compounds that favorably act on RXRs over retinoic acid receptors (RARs). Noteworthy examples of such compounds are bicyclic benzyl, pyridinyl, thiophene, furanyl, pyrrole, and various derivatives of polyenoic acids. His work in this area provides methods employing these compounds for selective modulation of RXR-mediated processes.
Additionally, Nadzan's patent titled "Dimer-selective RXR modulators and methods for their use" presents dimer-selective RXR modulator compounds with agonist, partial agonist, and antagonist activities. These modulators are invaluable for both RXR homodimers and heterodimers, alongside pharmaceutical compositions that incorporate these compounds for therapeutic applications.
Career Highlights
Throughout his career, Alex M Nadzan has been associated with prominent companies in the pharmaceutical sector, including Ligand Pharmaceuticals, Inc. and Abbott Laboratories Corporation. His roles within these organizations have allowed him to contribute to crucial developments in drug discovery and molecular biology.
Collaborations
Nadzan's innovative journey has been enhanced through collaborations with esteemed colleagues, including Marcus F Boehm and Chan Kou Hwang. These partnerships have fostered significant research advancements in RXR modulation, further showcasing the collaborative spirit prevalent in the scientific community.
Conclusion
Alex M Nadzan's contributions to retinoid research through his 17 patents exemplify his dedication to innovation in the field. His focus on RXR-selective compounds has the potential to revolutionize therapeutic strategies for various diseases. As the landscape of molecular biology continues to evolve, Nadzan's groundbreaking work will likely remain a cornerstone for future advancements in this critical area of research.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.