The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 1992

Filed:

Aug. 23, 1990
Applicant:
Inventors:

Alex M Nadzan, Libertyville, IL (US);

James F Kerwin, Mundelein, IL (US);

Chun W Lin, Wood Dale, IL (US);

Assignee:

Abbott Laboratories, Abbott Park, IL (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
H01N / ; C07D / ;
U.S. Cl.
CPC ...
514307 ; 514309 ; 514311 ; 514314 ; 514365 ; 514374 ; 514376 ; 514381 ; 514382 ; 514397 ; 514406 ; 514407 ; 514414 ; 514419 ; 546307 ; 546309 ; 546311 ; 546314 ; 548181 ; 548213 ; 548215 ; 548225 ; 548243 ; 548251 ; 548252 ; 548336 ; 548374 ; 548454 ; 548455 ; 548484 ; 548491 ;
Abstract

A compound of the formula: ##STR1## wherein R.sub.1 and R.sub.2 are substituents; R.sub.6 is hydrogen, loweralkyl, cycloalkyl, loweralkenyl, arylalkyl, (substituted aryl)alkyl, or (heterocyclic)alkyl; B is a bond, an alkylene group, an alkenylene group, an alkadienylene group or a heteroatom containing linking group; D is a substituted acyl group or tetrazolyl; Z is CO, C(S) or S(O).sub.2 ; Ar is a heterocyclic group; and n is 1 to 3. Also disclosed are a composition and a method for antagonizing CCK, a composition and method for treating or preventing gastrointestinal, central nervous, appetite regulating and pain regulating systems, a composition and method for treating or preventing hyperinsulinemia, methods of making the compounds and intermediates useful in making the compounds.


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