Company Filing History:
Years Active: 2020-2025
Title: Alex Franzusoff: Innovator in Cancer Immunotherapy
Introduction
Alex Franzusoff is a prominent inventor based in El Granada, CA (US), known for his significant contributions to the field of cancer immunotherapy. With a total of 8 patents, he has developed innovative methods and compositions aimed at improving the detection and treatment of cancer.
Latest Patents
Franzusoff's latest patents include groundbreaking work on compositions and methods for the identification of antigen-specific T cells. His inventions involve antigenic peptide-MHC complexes, referred to as comPACT polypeptides and comPACT polynucleotides. These patents disclose methods for producing such complexes and libraries of comPACT polynucleotides and polypeptides, which are exemplary in capturing cancer neoepitope-reactive T cells with high accuracy. Additionally, he has developed dual particle detection approaches that enhance the sensitivity and specificity of neoantigen-specific T cell detection. His work also includes signal-to-noise ratio analysis of isolated T cells, further improving the detection of neoantigen-specific T cells.
Another notable patent focuses on compositions and methods for the treatment of cancer using a CD8 engineered T cell therapy. This involves compositions and methods for a neoTCR-based cell therapy that utilizes a CD8 expression construct, showcasing his commitment to advancing cancer treatment methodologies.
Career Highlights
Throughout his career, Alex Franzusoff has worked with notable companies in the biotechnology sector, including Pact Pharma, Inc. and Adoc Ssf, LLC. His work in these organizations has allowed him to push the boundaries of cancer research and therapy.
Collaborations
Franzusoff has collaborated with esteemed colleagues such as Kyle Jacoby and Barbara Sennino, contributing to a rich environment of innovation and research in cancer immunotherapy.
Conclusion
Alex Franzusoff's contributions to cancer immunotherapy through his patents and collaborations highlight his role as a leading inventor in the field. His innovative approaches continue to pave the way for advancements in cancer treatment and detection.