Horsham, United Kingdom

Alastair Denholm

This inventor holds 2 USPTO granted patents, plus 1 CIPO patent. Top assignee: Novartis Ag. Active years: 2007-2008.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Alastair Denholm. Retrieved from https://idiyas.com/inventor/alastair-denholm

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile


% Patents Active = 50.0


Average Co-Inventor Count = 5.0

ph-index = 2

Forward Citations = 9(Granted Patents)


Location History:

  • Rochestown, IE (2007)
  • Horsham, GB (2008)

Company Filing History:


Years Active: 2007-2008

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2 patents (USPTO):Explore Patents

Title: Alastair Denholm: Innovator in Pharmaceutical Chemistry

Introduction

Alastair Denholm is a notable inventor based in Horsham, GB. He has made significant contributions to the field of pharmaceutical chemistry, particularly in the development of compounds that target specific enzymes related to inflammatory diseases. His work has led to the filing of multiple patents, showcasing his innovative approach to drug development.

Latest Patents

Denholm holds 2 patents that focus on the use of naphthyridine derivatives as phosphodiesterase type 4 (PDE4) inhibitors. His latest patents include:

1. [1,7]naphthyridines as PDE4 inhibitors - This patent describes compounds that are useful for treating conditions mediated by phosphodiesterase type 4 or the down-regulation or inhibition of TNF-α release, particularly in obstructive or inflammatory airways diseases. The patent also details pharmaceutical compositions containing these compounds and the processes for their preparation.

2. Naphthyridine derivatives, their preparation and their use as phosphodiesterase isoenzyme 4 (PDE4) inhibitors - This invention relates to compounds where R is a monovalent aromatic group having up to 10 carbon atoms, and R is a cycloaliphatic group having up to 8 ring carbon atoms. The patent outlines compositions containing these compounds, methods for their preparation, and their use as pharmaceuticals.

Career Highlights

Denholm is currently employed at Novartis AG, a leading global healthcare company. His role involves research and development in the pharmaceutical sector, where he applies his expertise in medicinal chemistry to create innovative therapeutic solutions.

Collaborations

Throughout his career, Denholm has collaborated with esteemed colleagues such as Thomas Hugo Keller and Clive McCarthy. These collaborations have further enhanced his research and contributed to the advancement of pharmaceutical innovations.

Conclusion

Alastair Denholm's work in the field of pharmaceutical chemistry exemplifies the impact of innovative thinking on healthcare solutions. His patents reflect a commitment to addressing significant medical challenges through scientific research and development.

Profile summary based on public USPTO records.
Data Sources: USPTO Patent Grant XML, Patent Center, EPO & CIPO • Normalized by IDiyas Innovation Graph. Methodology & provenance architecturePlease report any incorrect information to [email protected]
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