Company Filing History:
Years Active: 2015-2017
Title: Alan O Perantoni: Innovator in Peptide-Based Therapeutics
Introduction
Alan O Perantoni is a distinguished inventor based in Fairfield, PA (US). He has made significant contributions to the field of peptide-based therapeutics, holding a total of 3 patents. His work focuses on innovative methods to inhibit specific protein signaling pathways, which are crucial in various disease processes.
Latest Patents
Among his latest patents is a peptide-based STAT inhibitor. This invention comprises a peptide or peptidomimetic that includes the amino acid sequence of the second helix of a STAT protein, or a variant of such sequence. The peptide or peptidomimetic consists of about 40 or fewer amino acids and binds to a STAT protein. This invention also outlines methods for inhibiting a STAT protein in a cell and treating or preventing diseases associated with STAT overexpression in a host. Another notable patent is a peptide-based inhibitor of interleukin-10 or interferon-gamma signaling. This invention includes a peptide or peptidomimetic based on conserved regions of IL10 or IFN-gamma receptor sequences, along with related compounds and compositions. It also describes methods for using these inventions to inhibit cytokine signaling.
Career Highlights
Alan O Perantoni is currently affiliated with the National Institutes of Health, a component of the US Department of Health & Human Services. His work at this prestigious institution allows him to contribute to groundbreaking research in the biomedical field.
Collaborations
Throughout his career, Alan has collaborated with notable colleagues, including Nadya Tarasova and Shunsuke Tanigawa. These collaborations have further enhanced the impact of his research and innovations.
Conclusion
Alan O Perantoni is a prominent figure in the realm of peptide-based therapeutics, with a focus on innovative solutions for inhibiting critical protein signaling pathways. His contributions continue to advance the field and hold promise for future medical applications.
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