Alan Engelman

Title: Alan Engelman: Innovator in Retroviral Research

Introduction

Alan Engelman is a prominent inventor based in Brookline, MA (US). He has made significant contributions to the field of retroviral research, holding a total of 2 patents. His work focuses on innovative methods and compositions that aim to inhibit retroviral integration and replication.

Latest Patents

Engelman’s latest patents include "Compositions and methods for inhibition of retroviruses." This patent describes methods and compositions that inhibit the activity of components of the SET complex or base excision repair enzymes, inducing autointegration of retroviral double-stranded nucleic acid. Another notable patent is "Episomally replicating lentiviral vectors." This invention is directed towards a lentiviral vector system designed for episomal replication of a desired gene, incorporating various vectors that contain essential genes for lentiviral function.

Career Highlights

Throughout his career, Engelman has worked with esteemed organizations such as Dana-Farber Cancer Institute Inc. and Children's Medical Center Corporation. His research has significantly advanced the understanding of retroviral mechanisms and potential therapeutic approaches.

Collaborations

Engelman has collaborated with notable colleagues, including Wolfgang Hofmann and Joseph G. Sodroski. These partnerships have further enriched his research endeavors and contributed to the scientific community's knowledge of retroviruses.

Conclusion

Alan Engelman is a key figure in the field of retroviral research, with a focus on innovative solutions to combat retroviral challenges. His patents and collaborations reflect his commitment to advancing scientific understanding and therapeutic options in this critical area of study.