The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 2015
Filed:
May. 18, 2009
Applicants:
Nan Yan, Boston, MA (US);
Alan Engelman, Brookline, MA (US);
Judy Lieberman, Brookline, MA (US);
Inventors:
Assignees:
Children's Medical Center Corporation, Boston, MA (US);
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); A61K 31/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/00 (2013.01); C12N 2740/16011 (2013.01); A81K 31/7105 (2013.01);
Abstract
Described herein are methods and compositions for the inhibition of retroviral integration and replication. The methods and compositions inhibit the activity of one or more components of the SET complex or base excision repair enzymes and induce autointegration of retroviral double-stranded nucleic acid.