Location History:
- Laguna Beach, CA (US) (1992 - 1993)
- Beaver, UT (US) (1998)
- Boston, MA (US) (2004)
- Wellesley, MA (US) (1997 - 2006)
- Dover, MA (US) (1997 - 2009)
Company Filing History:
15 out of 790 
4 out of 832,891 Years Active: 1992-2009
Title: Innovations and Contributions of Alan E Smith in Viral Therapeutics
Introduction
Alan E Smith is a notable inventor hailing from Dover, MA, whose contributions to the field of viral therapeutics are marked by an impressive portfolio of 19 patents. His work mainly revolves around improving methods for the purification of viruses, which holds significant implications for therapeutic applications, especially in gene therapy.
Latest Patents
Among his latest inventions, two patents stand out: "Purification of adenovirus and AAV" and "Adenovirus vectors for gene therapy." The first patent outlines an innovative method for purifying large quantities of active adenovirus and adeno-associated virus (AAV), emphasizing the need for minimal damage to viral surface components during purification. This advance allows for the efficient and rapid purification of infectious viruses, which can be utilized in gene transfer and therapy procedures. The second patent focuses on gene therapy vectors specifically beneficial for treating cystic fibrosis. These vectors play a crucial role in enhancing the delivery of genes into target cells.
Career Highlights
Throughout his career, Alan has made significant strides while working at leading biotechnology companies, including the notable Genzyme Corporation. His efforts have not only led to advancements in viral purification and gene therapy but have also set new standards in the therapeutic use of viral vectors.
Collaborations
Alan E Smith has collaborated with talented individuals in his field, including Richard J Gregory and Donna Armentano. These partnerships have fostered innovative research and development, resulting in patents that could potentially revolutionize the way gene therapies are approached and implemented.
Conclusion
Alan E Smith's contributions to the field of viral therapeutics through his patents on purification methods and gene therapy vectors have significantly impacted medical science. His work paves the way for advanced therapeutic solutions, particularly in the realm of genetic disorders, reflecting a commitment to innovation and health improvement.