The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2006
Filed:
Jul. 02, 1993
Richard Gregory, Ayer, MA (US);
Seng H. Cheng, Boston, MA (US);
Alan Smith, Wellesley, MA (US);
Sucharita Paul, Grafton, MA (US);
Kathleen M. Hehir, Grafton, MA (US);
John Marshall, Milford, MA (US);
Richard Gregory, Ayer, MA (US);
Seng H. Cheng, Boston, MA (US);
Alan Smith, Wellesley, MA (US);
Sucharita Paul, Grafton, MA (US);
Kathleen M. Hehir, Grafton, MA (US);
John Marshall, Milford, MA (US);
Genzyme Corporation, Cambridge, MA (US);
Abstract
Disclosed are full length isolated DNAs encoding cystic fibrosis transmembrane conductance regulator (CFTR) protein and a variety of mutants thereof. Also disclosed are antibodies specific for various CFTR domains and methods for their production. Expression of CFTR from cells transformed with these CFTR genes or cDNAs demonstrate surprising CFTR intracellular distributions and results thereby providing for new diagnostic and therapeutic procedures.