Akira Mashimo

Title: Akira Mashimo: Innovator in Pharmaceutical Formulations

Introduction

Akira Mashimo is a prominent inventor based in Osaka, Japan. He has made significant contributions to the field of pharmaceutical formulations, holding a total of 5 patents. His work focuses on improving the stability and dissolution profiles of various compounds, which is crucial in the development of effective medications.

Latest Patents

Among his latest patents, one notable invention is a preparation containing 6,7-unsaturated-7-carbamoyl morphinan derivatives. This solid preparation enhances the dissolution profile and stability of the morphinan derivative. Specifically, when combined with croscarmellose sodium and ferric oxide, the dissolution rate after 15 minutes exceeds 85%, while also improving light stability. Another significant patent involves a manufacturing process for formulations that achieve improved content uniformity. This method ensures that the standard deviation of the active ingredient content in the solid formulation is 5% or less by utilizing excipients with a median particle size significantly larger than that of the active ingredient.

Career Highlights

Akira Mashimo is associated with Shionogi Company Limited, a well-respected organization in the pharmaceutical industry. His innovative approaches have contributed to the company's reputation for developing high-quality medications.

Collaborations

He has collaborated with notable coworkers, including Shunji Ichio and Yoshinori Tamura, who have also made significant contributions to the field.

Conclusion

Akira Mashimo's work in pharmaceutical formulations exemplifies the importance of innovation in medicine. His patents reflect a commitment to enhancing drug efficacy and stability, which ultimately benefits patients worldwide.