This inventor holds 2 USPTO granted patents. Top assignees: Chemo-Sero-Therapeutic Research Institute, Science and Technology Agency, Minister's Secretariat Director of. Active years: 1988-1998.
Company Filing History:
2 out of 151 
1 out of 1 Years Active: 1988-1998
Title: Akio Toh-e: Innovator in Genetic Engineering
Introduction
Akio Toh-e is a notable inventor based in Hiroshima, Japan. He has made significant contributions to the field of genetic engineering, holding 2 patents that showcase his innovative work. His inventions have implications for both research and practical applications in biotechnology.
Latest Patents
Toh-e's latest patents include a shuttle vector that contains both a yeast gene and an E. coli gene. This shuttle vector carries the expression control region of the acid phosphatase gene of yeast, allowing for recombination with various genes under the control of the phosphatase promoter. This invention is particularly useful in genetic engineering industries. Another significant patent is a recombinant plasmid inserted with the Hepatitis B virus gene. This plasmid vector also contains a yeast gene and an E. coli gene, along with the expression control region of the repressible acid phosphatase gene of yeast. The transformed yeast, prepared by transforming a yeast with this recombinant plasmid, can produce Hepatitis B virus surface antigen on a large scale. This antigen has the same immunological properties as the natural antigen from human blood plasma, making it valuable for the preparation of Hepatitis B virus vaccines and diagnostic reagents.
Career Highlights
Throughout his career, Akio Toh-e has worked with esteemed organizations such as the Chemo-Sero-Therapeutic Research Institute and the Science and Technology Agency, where he served as the Minister's Secretariat Director. His work in these institutions has furthered advancements in medical and biotechnological research.
Collaborations
Toh-e has collaborated with notable individuals in his field, including Atsushi Miyanohara and Kenichi Matsubara. These collaborations have likely contributed to the success and impact of his inventions.
Conclusion
Akio Toh-e's contributions to genetic engineering through his innovative patents demonstrate his significant role in advancing biotechnology. His work continues to influence the development of medical solutions and research methodologies.