Akio Takimoto

Title: Akio Takimoto: Innovator in Glycomic Analysis and Enzyme Modification

Introduction

Akio Takimoto is a prominent inventor based in Amagasaki, Japan. He has made significant contributions to the fields of glycomic analysis and enzyme modification, holding a total of 5 patents. His work has implications in various scientific and medical applications, particularly in the analysis of glycoproteins and the development of modified enzymes.

Latest Patents

One of Takimoto's latest patents is a method of serum pre-treatment for glycomic analysis. This invention provides a means for pre-treatment in glycomic analysis of glycoproteins, utilizing a specific salt as a protein solubilizer. This method allows for the efficient release of oligosaccharides from samples through reductive alkylation and/or digestion by proteinase. Another notable patent involves an L-methionine γ-lyase with modified function. This enzyme is structurally stabilized and has been analyzed using X-ray crystallography. The invention includes DNA sequences encoding these enzymes and processes for their production, with potential applications in medicinal preparations, particularly anticancer agents.

Career Highlights

Throughout his career, Akio Takimoto has worked with notable organizations, including Shionogi Company Limited and Hokkaido University. His experience in these institutions has contributed to his expertise in the field and has facilitated his innovative research.

Collaborations

Takimoto has collaborated with esteemed colleagues such as Kenji Mitsushima and Takayasu Sonoyama. These partnerships have likely enhanced his research and development efforts, leading to impactful inventions.

Conclusion

Akio Takimoto's contributions to glycomic analysis and enzyme modification highlight his role as a significant inventor in the scientific community. His innovative patents and collaborations reflect his dedication to advancing research in these important fields.