The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2006
Filed:
Aug. 24, 2001
Kenji Inagaki, Okayama, JP;
Hidehiko Tanaka, Okayama, JP;
Akio Takimoto, Amagasaki, JP;
Tomoaki Takakura, Amagasaki, JP;
Shintaro Misaki, Osaka, JP;
Kenji Inagaki, Okayama, JP;
Hidehiko Tanaka, Okayama, JP;
Akio Takimoto, Amagasaki, JP;
Tomoaki Takakura, Amagasaki, JP;
Shintaro Misaki, Osaka, JP;
Shionogi & Co., Ltd., Osaka, JP;
Abstract
An L-methionine γ-lyase having modified function which is obtained by structurally stabilizing natural L-methionine γ-lyase by analyzing the structure of crystals thereof by using X-ray, estimating an amino acid sequence concerning its substrate specificity and varying amino acid residue thereof; enzymes comprising a protein constituting the L-methionine γ-lyase having modified function or its multimer (preferably its tetramer); DNA sequences encoding these enzymes; a process for producing these enzymes; and medicinal preparations (preferably anticancer agent) containing these enzymes.