Akio Sugihara

Title: Akio Sugihara: Innovator in Pharmaceutical Composition

Introduction

Akio Sugihara is a notable inventor based in Shizuoka, Japan. He has made significant contributions to the field of pharmaceuticals, particularly in the development of innovative drug formulations. With a total of 4 patents to his name, Sugihara's work focuses on enhancing the efficacy and stability of pharmaceutical compositions.

Latest Patents

One of Sugihara's latest patents is a pharmaceutical composition for oral administration. This invention comprises a modified release portion containing tamsulosin or a pharmaceutically acceptable salt thereof, along with an immediate release portion containing solifenacin or a pharmaceutically acceptable salt thereof and a hydrophilic substance. The dissolution rate of each drug, especially solifenacin, is comparable to current single drug formulations, achieving a maximum percentage of drug dissolution of 90% or more. This formulation offers a bioavailability equivalent to existing single drug formulations.

Another significant patent involves the composition of solifenacin or its salt for use in solid formulations. This solid pharmaceutical preparation is designed to be stable and resistant to decomposition over time when utilized in clinical settings. The preparation reveals that solifenacin in an amorphous form can lead to drug decomposition. Therefore, the composition includes solifenacin or its salt in a crystalline form, along with a process for producing the composition and a medicinal composition for solid pharmaceutical preparations that contains solifenacin and an amorphization inhibitor.

Career Highlights

Throughout his career, Akio Sugihara has worked with prominent companies in the pharmaceutical industry, including Astellas Pharma GmbH and Yamanouchi Pharmaceutical Company Ltd. His experience in these organizations has contributed to his expertise in drug formulation and development.

Collaborations

Sugihara has collaborated with notable colleagues such as Takehiko Yasuji and Kazuhiro Sako. These partnerships have further enriched his work and innovations in the pharmaceutical field.

Conclusion

Akio Sugihara's contributions to pharmaceutical compositions demonstrate his commitment to advancing drug formulation technology. His innovative patents reflect a deep understanding of pharmaceutical science and a dedication to improving patient outcomes.