The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2015
Filed:
Feb. 02, 2010
Takehiko Yasuji, Tokyo, JP;
Noriyuki Kinoshita, Tokyo, JP;
Hiroyuki Yoshino, Tokyo, JP;
Shuuya Kawahama, Tokyo, JP;
Kazuhiro Sako, Tokyo, JP;
Akio Sugihara, Shizuoka, JP;
Takehiko Yasuji, Tokyo, JP;
Noriyuki Kinoshita, Tokyo, JP;
Hiroyuki Yoshino, Tokyo, JP;
Shuuya Kawahama, Tokyo, JP;
Kazuhiro Sako, Tokyo, JP;
Akio Sugihara, Shizuoka, JP;
ASTELLAS PHARMA INC., Tokyo, JP;
Abstract
The present invention relates to a pharmaceutical composition for oral administration comprising a modified release portion containing tamsulosin or a pharmaceutically acceptable salt thereof, and an immediate release portion containing solifenacin or a pharmaceutically acceptable salt thereof and a hydrophilic substance. In the pharmaceutical composition, the dissolution rate of each drug (in particular, solifenacin contained in the immediate release portion) is similar to those of the current single drug formulations, and the maximum percentage of drag dissolution of each drug (in particular, solifenacin contained in the immediate release portion) is 90% or more. Therefore, the pharmaceutical composition is a single formulation (i.e., a combined formulation) with a bioavailability equivalent to those of the current single drug formulations.