Tokushima, Japan

Akihiro Shimabayashi


Average Co-Inventor Count = 2.8

ph-index = 5

Forward Citations = 49(Granted Patents)


Company Filing History:


Years Active: 1990-2010

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7 patents (USPTO):Explore Patents

Title: Akihiro Shimabayashi: Innovator in Pharmaceutical Chemistry

Introduction

Akihiro Shimabayashi is a notable inventor based in Tokushima, Japan. He has made significant contributions to the field of pharmaceutical chemistry, particularly in the development of processes for producing valuable compounds. With a total of 7 patents to his name, Shimabayashi's work has had a considerable impact on the industry.

Latest Patents

One of his latest patents is titled "Process for producing penam compound useful for preparing tazobactam." This invention aims to provide an industrially advantageous process that remarkably suppresses the generation of an undesirable by-product, cepham compound. By reacting diphenylmethyl 2β-bromomethyl-2α-methylpenam-3α-carboxylate (BMPB) with 1,2,3-triazole in a halogenated hydrocarbon solvent at -5°C or lower, the desired diphenylmethyl 2α-methyl-2β-[(1,2,3-triazol-1-yl)methyl]penam-3α-carboxylate (TMPB) can be efficiently produced. Another significant patent is for "Anhydrous crystal of β-lactam compound and method for preparation thereof." This invention provides anhydrous crystals of a β-lactam compound, produced by heating an aqueous solution of a salt of the β-lactam compound and adjusting the pH to 3 or lower, ensuring excellent storage stability.

Career Highlights

Throughout his career, Akihiro Shimabayashi has worked with prominent companies in the pharmaceutical sector, including Otsuka Pharmaceutical Co., Ltd. and Taiho Pharmaceutical Company Limited. His expertise in pharmaceutical chemistry has allowed him to develop innovative processes that enhance the efficiency and effectiveness of drug production.

Collaborations

Shimabayashi has collaborated with notable colleagues in his field, including Kiyotoshi Matsumura and Ichiro Kawahara. These collaborations have contributed to the advancement of pharmaceutical research and development.

Conclusion

Akihiro Shimabayashi is a distinguished inventor whose work in pharmaceutical chemistry has led to significant advancements in drug production processes. His innovative patents and collaborations highlight his commitment to improving the efficiency and effectiveness of pharmaceutical compounds.

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