Location History:
- Dexter, MI (US) (2003 - 2006)
- Ann Arbor, MI (US) (2006)
Company Filing History:
Years Active: 2003-2006
Title: Ahmed A K Hasan: Innovator in Thrombin Inhibition
Introduction
Ahmed A K Hasan is a notable inventor based in Ann Arbor, MI (US). He has made significant contributions to the field of biochemistry, particularly in the development of peptide analogs that serve as selective inhibitors of thrombin and related cell activation processes. With a total of 3 patents, his work has the potential to impact medical treatments for conditions related to platelet aggregation and thrombosis.
Latest Patents
One of his latest patents is titled "Synthetic peptide analogs of Arg-Pro-Pro-Gly-Phe as selective inhibitors of thrombin and thrombin activation of protease activated receptors 1 and 4." This invention relates to compounds and methods for inhibiting human platelet aggregation, thrombosis, and cell activation mediated by PAR1 and PAR4 using peptide analogs of Arg-Pro-Pro-Gly-Phe that contain one or more amino acid substitutions. The invention also includes screening methods for identifying compounds that inhibit thrombin-mediated activities.
Another significant patent is "Bradykinin analogs as selective inhibitors of cell activation." This invention provides bradykinin peptide analogs, compositions, and methods of inhibiting thrombin-induced platelet and other cell activation. The bradykinin analogs comprise single or multiple peptide segments. The invention also provides a method for identifying compounds that selectively inhibit thrombin-induced platelet and other cell activation.
Career Highlights
Ahmed A K Hasan has worked at the University of Michigan, where he has been involved in groundbreaking research that has led to his innovative patents. His work has been instrumental in advancing the understanding of thrombin's role in various biological processes.
Collaborations
He has collaborated with notable professionals in his field, including Alvin H Schmaier, which has further enriched his research and development efforts.
Conclusion
Ahmed A K Hasan's contributions to the field of thrombin inhibition through his innovative patents highlight his role as a significant inventor in biochemistry. His work continues to pave the way for advancements in medical treatments related to platelet aggregation and thrombosis.