Belmont, CA, United States of America

Adrian Lobito


 

Average Co-Inventor Count = 7.0

ph-index = 1


Company Filing History:


Years Active: 2022-2024

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2 patents (USPTO):Explore Patents

Title: Adrian Lobito: Innovator in Recombinant Protein Technology

Introduction

Adrian Lobito is a notable inventor based in Belmont, California, recognized for his contributions to the field of recombinant protein technology. With a total of 2 patents, Lobito has made significant strides in developing innovative solutions for medical applications.

Latest Patents

One of Lobito's latest patents is focused on a recombinant chimeric protein designed for selectins targeting. This invention discloses a recombinant protein known as the PSGL-1-NRL chimeric protein, which comprises a Selectin Binding domain and a non-covalent dimerization domain, specifically a leucine zipper. The chimeric protein also includes a covalent dimerization domain with at least one cysteine, allowing it to form a disulfide bridge with another chimeric protein to create a homodimer. The PSGL-1 domain corresponds to the extracellular region of Human PSGL-1, particularly the selectin binding region of the mature protein. This protein is efficiently expressed in a mammalian system and is correctly post-translationally modified, being sulfated, O-linked glycosylated, and sialylated. It binds P, E, and L selectin, enabling in vivo and in vitro targeting for diagnostic or therapeutic purposes.

Career Highlights

Throughout his career, Adrian Lobito has worked with reputable companies, including Bracco Suisse and Bracco Suisse SA. His experience in these organizations has contributed to his expertise in the field of biotechnology and protein engineering.

Collaborations

Lobito has collaborated with notable professionals in his field, including Federico Maisano and Federico Crivellin. These collaborations have likely enhanced his research and development efforts in recombinant protein technology.

Conclusion

Adrian Lobito's innovative work in recombinant protein technology showcases his commitment to advancing medical science. His patents and collaborations reflect his significant contributions to the field, making him a noteworthy inventor in the biotechnology sector.

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