This inventor holds 5 USPTO granted patents and 12 published patent applications, plus 1 CIPO patent and 2 EPO patents. Top assignees: Tel Aviv University, Leland Stanford Junior University. Active years: 2013-2026.
Location History:
- Moshav Nir-Tzvi, IL (2013)
- Palo Alto, CA (US) (2020 - 2024)
- Hod Hasharon, IL (2024)
Company Filing History:
Years Active: 2013-2026
Title: Adi Barzel: Innovator in Gene Targeting and Homing Endonucleases
Introduction
Adi Barzel is a prominent inventor based in Moshav Nir-Tzvi, Israel. He has made significant contributions to the field of genetic engineering, particularly in the areas of gene targeting and homing endonucleases. With a total of 5 patents, Barzel's work is paving the way for advancements in immunotherapy and genetic research.
Latest Patents
Barzel's latest patents include groundbreaking inventions that focus on gene targeting. The first patent, titled "Recombination activating gene (RAG) induced V(D)J gene targeting," relates to methods for the targeted insertion of nucleic acid sequences into a target genomic locus of mammalian cells. This invention utilizes nucleic acid cassettes that comprise the sequences of interest and recognition signal sequences (RSS) to facilitate RAG-catalyzed recombination. The implications of this work extend to immunotherapy, providing new avenues for treatment.
The second patent, "Method for searching for homing endonucleases, their genes and their targets," describes a computer-implemented method for generating nucleotide sequences that contain candidate homing endonuclease genes (HEGs). This method involves searching a database for amino acid sequences that have a homology level with predetermined HEGs. The results of this search are then used to generate HEG-containing sequences, which can be crucial for various genetic applications.
Career Highlights
Adi Barzel is affiliated with Tel Aviv University, where he continues to engage in innovative research. His work has garnered attention in the scientific community, contributing to advancements in genetic engineering and therapeutic applications.
Collaborations
Barzel collaborates with notable colleagues, including Martin Kupiec and Carmel Pundak-Mintz. These partnerships enhance the scope and impact of his research, fostering a collaborative environment for scientific discovery.
Conclusion
Adi Barzel's contributions to the field of genetic engineering through his patents and research at Tel Aviv University highlight his role as an influential inventor. His work not only advances scientific knowledge but also opens new possibilities for therapeutic applications in medicine.