Alleroed, Denmark

Adam Paul Chambers


Average Co-Inventor Count = 8.0

ph-index = 1


Company Filing History:


Years Active: 2023

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1 patent (USPTO):Explore Patents

Title: The Innovative Contributions of Adam Paul Chambers

Introduction

Adam Paul Chambers is a notable inventor based in Alleroed, Denmark. He has made significant strides in the field of obesity treatment through his innovative research and development. His work focuses on compounds that target specific areas in the brain responsible for regulating body weight.

Latest Patents

Chambers holds a patent for "Compounds for treatment of obesity." This invention involves a construct that comprises a compound targeting areas in the brain involved in the regulation of body weight, along with an allosteric ligand to a receptor located in the blood-brain barrier (BBB). The patent also covers compositions and uses of such constructs, particularly in the prevention or treatment of overweight and obesity. Preferred compounds for regulating body weight include GLP-1 receptor agonists (GLP-1RA), while preferred receptors located in the BBB include the transferrin receptor (TfR). Notably, exemplary fusions and conjugates of GLP-1 RAs and anti TfR-Fab's demonstrate increased binding to brain regions expressing the GLP-1 receptor compared to inactive control Fab's. In vivo studies in mice confirm that the active construct leads to a greater reduction in food intake and weight loss compared to the inactive version.

Career Highlights

Chambers is currently associated with Novo Nordisk A/S, a leading global healthcare company specializing in diabetes care and other chronic conditions. His work at Novo Nordisk has allowed him to contribute to groundbreaking research in obesity treatment.

Collaborations

Chambers collaborates with talented colleagues, including Nikolaj Kulahin Roed and Michael Paolo Bastner Sandrini. Their combined expertise enhances the innovative potential of their projects.

Conclusion

Adam Paul Chambers is a pioneering inventor whose work in obesity treatment is making a significant impact in the field of healthcare. His innovative approaches and collaborations are paving the way for future advancements in the treatment of obesity.

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