Aaron Klug

Cambridge, United Kingdom

Aaron Klug

Nobel Prize



Average Co-Inventor Count = 3.2

ph-index = 9

Forward Citations = 1,201(Granted Patents)


Location History:

  • Cambridge, GB (1999 - 2015)
  • London, GB (2015 - 2020)

Company Filing History:


Years Active: 1999-2020

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22 patents (USPTO):Explore Patents

Title: Innovations of Aaron Klug: A Journey Through Patents and Collaboration

Introduction

Aaron Klug, a prominent figure in the scientific community, is based in Cambridge, GB. He holds an impressive 22 patents that reflect his dedication to innovation and his contributions to the field of molecular biology. His work has greatly influenced the understanding and manipulation of genetic material, positioning him as a key inventor in modern science.

Latest Patents

Among his most recent patents, Klug has developed methods for polypeptide targeting to mitochondria. This innovation provides methods for delivering non-mitochondrial proteins to mitochondria by utilizing nucleic acid constructs that comprise a coding sequence encoding a DNA-binding polypeptide, which is fused with a mitochondrial targeting sequence (MTS) and a nuclear export signal (NES). The encoded proteins demonstrated successful delivery of DNA-binding proteins to the mitochondrion. Another significant contribution includes the disclosure of libraries of DNA sequences encoding zinc finger binding motifs for display on a particle. This patent details methods for designing zinc finger binding polypeptides tailored for binding to specific target sequences, along with numerous applications in vitro and in vivo.

Career Highlights

Aaron Klug’s career features significant engagements with respected organizations, including Gendaq Limited and the Medical Research Council. His work in these institutions has been pivotal in advancing the frontiers of genetic research and therapeutic applications. The breadth of his experience reflects his versatility and commitment to scientific progress.

Collaborations

Throughout his career, Klug has collaborated with notable figures such as Yen Choo and Mark Isalan. These partnerships have facilitated groundbreaking research and innovation, enhancing the impact of his contributions to genetics and molecular science.

Conclusion

Aaron Klug's extensive patent portfolio and collaborative efforts underscore his status as a trailblazer in the field of molecular biology. His work not only showcases his inventive spirit but also significantly contributes to advancements in genetic research, paving the way for future innovations that can alter our understanding of biological systems.

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