Company Filing History:
Years Active: 2010-2013
Title: Aare Abroi: Innovating in Viral Expression Technologies
Introduction
Aare Abroi, an accomplished inventor based in Tartu, Estonia, has made significant contributions to the field of molecular biology through his innovative patents. With a focus on viral expression plasmids, his work aims to enhance the production of proteins, antibodies, enzymes, and virus-like particles for various applications including cell-based assays.
Latest Patents
Aare Abroi holds two notable patents that represent advancements in the stable maintenance and replication of plasmids. The first patent titled "Viral expression plasmids for production of proteins, antibodies, enzymes, virus-like particles and for use in cell-based assays" reveals how the EBV FR-element containing EBNA1 multimeric binding sites can provide stable maintenance replication functions to the mouse polyomavirus (PyV) core origin plasmids with the assistance of BPV-1 E2 protein and PyV large T-antigen (LT). This innovation is crucial for developing efficient expression systems in various cell lines.
The second patent, "Vectors, cell lines and their use in obtaining extended episomal maintenance replication of hybrid plasmids and expression of gene products," demonstrates that the BPV-1 E2 protein-dependent minichromosome maintenance element (MME) can also facilitate the stable maintenance of the mouse polyomavirus core origin plasmids. Notably, the MME dependent plasmids show only a 6% loss per generation, indicating a significant potential for stable genetic maintenance without selection pressure.
Career Highlights
Throughout his career, Aare has worked with several respected organizations, including Kosagen Cell Factory and Icosagen Cell Factory. His tenure in these companies underscores his dedication to advancing biotechnological applications and supports the development of cutting-edge solutions for the scientific community.
Collaborations
Aare Abroi has collaborated with prominent figures in the field, including Toomas Silla and Ingrid Tagen. These partnerships have likely facilitated knowledge sharing and innovation, contributing to the progress of their joint ventures in viral expression technologies.
Conclusion
Aare Abroi stands out as a visionary inventor whose patents are shaping the future of molecular biology and biotechnology. His research and collaborations exemplify the importance of innovation in developing reliable and efficient systems for protein production and genetic research. With his work, Aare continues to pave the way for advancements in scientific and medical applications.